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Anti-dsDNA refers to antibodies directed against double-stranded DNA
Anti-dsDNA refers to antibodies directed against double-stranded DNA. These antibodies are highly specific for systemic lupus erythematosus (SLE), an autoimmune disease where the immune system attacks the body's own tissues and organs.
Anti-dsDNA contributes to the development of symptoms by forming immune complexes that deposit in tissues, causing inflammation. Common manifestations include:
Although primarily linked to SLE, low levels of anti-dsDNA may sometimes be seen in:
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