Transferrin Saturation is a clinical measure of how much iron is bound to the protein transferrin, which transports iron in the blood. It is expressed as a percentage and calculated using the ratio of serum iron to total iron-binding capacity (TIBC). Transferrin saturation provides insight into the body's iron status and helps assess iron metabolism.

Why It Should Be Tested: Transferrin saturation is an essential diagnostic tool for evaluating iron-related disorders. It helps detect conditions such as iron deficiency anemia, where levels are low, or iron overload disorders like hereditary hemochromatosis, where levels are abnormally high. Early detection through transferrin saturation tests allows for timely treatment, preventing complications like organ damage associated with iron imbalances.